For the millions of people living with genetic diseases like muscular dystrophy and inherited liver disorders, one of the ...

During her chemistry Nobel Prize lecture in 2018, Frances Arnold said, “Today we can for all practical purposes read, write, and edit any sequence of DNA, but we cannot compose it.” That isn’t true ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

This new patented toolbox, complementing - and for certain applications surpassing - CRISPR, is now available for researchers and industry in the field of genome engineering. The results are reported ...

A compact Cas12f nuclease shows high editing efficiency in human cells, with structural insights enabling an engineered variant potentially suited for future AAV‑compatible delivery.

The CRISPR-Cas gene-editing system has long been the focus of research as a promising tool in genome editing. However, the ...

With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot happening in the genome editing field. By Amber Dance/Knowable Magazine Published Jan 26, ...

Many foundational research technologies have transformed cellular therapies, moving treatments from concept to clinic. In the past decade, chimeric antigen receptors (CAR) and genome editing are two ...

A research team headed by the University of Zurich has developed a powerful new method to precisely edit DNA by combining cutting-edge genetic engineering with artificial intelligence. The work has ...

We have been lauding the benefits of CRISPR for a couple of years, and how different it is from GMOs—and how the perception from consumers is being managed. And it appears that 2019 may well be CRISPR ...